What is Manyolo Male Enhancement? Manyolo Male Enhancement is a dietary supplement designed to help men enhance their sexual performance, increase libido, and improve overall male health. Marketed primarily as a natural supplement, it claims to use a blend of ingredients that support better circulation, hormone production, and stamina. Manyolo is typically available in the form of capsules, and is marketed as a fast-acting, safe solution to common male health issues such as erectile dysfunction, low libido, and fatigue.